The Office for National Statistics found it contained the highest proportion of deprived areas, followed by West Bromwich in the West Midlands.
Guildford in Surrey was the least deprived town.
The study considered factors such as income, employment, health, education, skills and training and crime.
It also looked at disability levels, access to housing and the built environment in cities and towns in England and Wales.
The north-west of England had five of the ten most deprived towns and cities, while the West Midlands had three of the top five.

North-west claims five out of 10 worst affected

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